CanRisk Tool

The CanRisk tool is a web interface to BOADICEA, the Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm, which is a risk prediction model used to calculate future breast and ovarian cancer risks in women. This is the first comprehensive model of its kind that allows for consistent breast cancer risk prediction in unaffected women on the basis of mutation screening information for rare (high risk and moderate risk) breast cancer genetic susceptibility variants, common cancer genetic susceptibility variants (combined SNP effects in terms of polygenic risk scores), explicit family history, personal lifestyle/hormonal/reproductive risk factors and mammographic density.

This work is supported by grants through Cancer Research UK, the European Union’s Horizon 2020 and Innovation programme, Genome Canada and a Wellcome Trust Collaborative Award.

Please see more details here on the Cancer Research-UK funded CanRisk programme.

CanRisk Team

Team Leaders

Development team at the Department of Public Health and Primary Care, University of Cambridge